D81.32 ICD 10 Code is a billable and specific code that can be used to indicate a diagnosis of Adenosine deaminase 2 deficiency for reimbursement purposes. The 2023 edition of the American ICD-10-CM code became effective on October 1, 2022.
Possible back-references that may be applicable or related to D81.32 ICD10 Code:
- D50-D89 Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- D80-D89 Certain disorders involving the immune mechanism
- D81 Combined immunodeficiencies
- D81.3 Adenosine deaminase [ADA] deficiency
- D81.8 Other combined immunodeficiencies
Present On Admission (POA Exempt)
D81.32 ICD 10 code is considered exempt from POA reporting
Clinical information about D81.32 ICD 10 code
Adenosine deaminase 2 (ADA2) deficiency is a disorder characterized by abnormal inflammation of various tissues. Signs and symptoms can begin anytime from early childhood to adulthood. The severity of the disorder also varies, even among affected individuals in the same family.
Inflammation is a normal immune system response to injury and foreign invaders (such as bacteria). However, ADA2 deficiency causes abnormal, unprovoked inflammation that can damage the body's tissues and organs, particularly blood vessels. (Inflammation of blood vessels is known as vasculitis.) Other tissues affected by abnormal inflammation can include the skin, gastrointestinal system, liver, kidneys, and nervous system. Depending on the severity and location of the inflammation, the disorder can cause disability or be life-threatening.
Signs and symptoms that can occur with ADA2 deficiency include fevers that are intermittent, meaning they come and go; areas of net-like, mottled skin discoloration called livedo racemosa; an enlarged liver and spleen (hepatosplenomegaly); and recurrent strokes affecting structures deep in the brain that can start in the first few years of life. In some people, ADA2 deficiency causes additional immune system abnormalities that increase the risk of bacterial and viral infections.
ADA2 deficiency is sometimes described as a form of polyarteritis nodosa (PAN), a disorder that causes inflammation of blood vessels throughout the body (systemic vasculitis). However, not all researchers classify ADA2 deficiency as a type of PAN.
The information in this box was provided by MedlinePlus.gov